Eph receptor signalling: from catalytic to non-catalytic functions
نویسندگان
چکیده
منابع مشابه
Non-catalytic functions of DNMT1.
Mammalian DNA methyltransferase 1 (DNMT1) is essential during early embryo development. Consistent with its key role in embryogenesis, depletion of this protein in adult somatic cells promotes severe cellular dysfunctions and cell death. DNMT1 contains a highly evolutionary conserved C-terminal catalytic DNA methyltransferase domain that is thought to be the responsible for the maintenance of C...
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Daily rhythms in gene expression play a critical role in the progression of circadian clocks, and are under regulation by transcription factor binding, histone modifications, RNA polymerase II (RNAPII) recruitment and elongation, and post-transcriptional mechanisms. Although previous studies have shown that clock-controlled genes exhibit rhythmic chromatin modifications, less is known about the...
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ژورنال
عنوان ژورنال: Oncogene
سال: 2019
ISSN: 0950-9232,1476-5594
DOI: 10.1038/s41388-019-0931-2