EP08.21: Neuropathologic changes associated to prenatal Zika virus infection: a correlation between prenatal ultrasound and postmortem findings
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چکیده
منابع مشابه
Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection
Pregnant women, and their fetal offspring, are uniquely susceptible to Zika virus and other microbial pathogens capable of congenital fetal infection. Unavoidable exposure to Zika virus in endemic areas underscores the need for identifying at-risk individuals, and protecting expecting mothers and their fetal offspring against prenatal infection. Here we show that primary Zika virus asymptomatic...
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In a recent paper in Cell Death and Disease, Di Cunto and co-workers found that infection of human neural progenitors (hNPCs) with Zika virus (ZIKV) induced transcriptional responses that were partly comparable to three different genetic mutations (CitK , Magoh , and conditional Elp3 /− mice), which result in microcephaly in mice. The highest overlap between these different conditions was found...
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Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neuro...
متن کاملRestrictive dermopathy and associated prenatal ultrasound findings: case report.
Restrictive dermopathy is a lethal autosomal recessive skin disease. Prenatal diagnosis has not yet been reported. We present a case of restrictive demography and describe the associated prenatal sonographic findings. A continuously open mouth was the most striking feature and this sonographic finding may be a marker of a skin disease.
متن کاملPrenatal diagnosis and postmortem findings of Neu-laxova syndrome.
Neu-laxova syndrome is a lethal, autosomal recessive condition associated with ectodermal abnormalities and other characteristic features, including microcephaly, marked intrauterine growth restriction, limb deformities, central nervous system malformations and abnormal facial features, consisting of severe proptosis with ectropion, hypertelorism, micrognathia, flattened nose, malformed ears, a...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics & Gynecology
سال: 2018
ISSN: 0960-7692
DOI: 10.1002/uog.19906