EP-2046: Modulation of radiation-induced oral mucositis (mouse) by dermatan sulfate
نویسندگان
چکیده
منابع مشابه
Radiation-Induced Oral Mucositis
Radiation-induced oral mucositis (RIOM) is a major dose-limiting toxicity in head and neck cancer patients. It is a normal tissue injury caused by radiation/radiotherapy (RT), which has marked adverse effects on patient quality of life and cancer therapy continuity. It is a challenge for radiation oncologists since it leads to cancer therapy interruption, poor local tumor control, and changes i...
متن کاملSingle-Dose Radiation-Induced Oral Mucositis Mouse Model
The generation of a self-resolved radiation-induced oral mucositis (RIOM) mouse model using the highest possibly tolerable single ionizing radiation (RT) dose was needed in order to study RIOM management solutions. We used 10-week-old male BALB/c mice with average weight of 23 g for model production. Mice were treated with an orthovoltage X-ray irradiator to induce the RIOM ulceration at the in...
متن کاملModulation of radiation and cadmium induced biochemical changes in mouse kidney by Emblica officinalis Linn
Background: Protective effect of Emblica against radiation and cadmium induced biochemical changes in mouse kidney has been studied. Materials and Methods: Adult male mice were divided into seven groups: I (shamirradiated), II (cadmium chloride), III (irradiated with 2 Gy gamma rays), IV (radiation and cadmium chloride), V (Cadmium chloride and Emblica), VI (radiation and Emblica), VII...
متن کاملRadiation therapy and chemotherapy-induced oral mucositis.
UNLABELLED Increasing the intensity of radiation therapy and chemotherapy in the management of cancer has increased the incidence of adverse effects, especially oral mucositis. AIM AND METHODS a bibliographical review was conducted on the definition of oral mucositis, its clinical findings, the incidence, its etiology, the pathophysiology, associated morbidity, prevention and treatment. RES...
متن کاملEvaluation of radiation-induced oral mucositis by optical coherence tomography.
PURPOSE Optical coherence tomography (OCT) imaging was evaluated to determine if radiation-induced mucosal damage could be noninvasively monitored in real time and correlated with histopathologic findings. EXPERIMENTAL DESIGN Female C3H mice, ages 7 to 9 weeks, four per group, were immobilized in a custom-made Lucite jig and received 0, 15, 22.5, and 25 Gy in a single fraction to their oral c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2016
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(16)33297-2