Enzyme–Iron Oxide Nanoassemblies: A Review of Immobilization and Biocatalytic Applications

In the search for new biotechnological advances, increasing attention is currently being paid to development of magnetic nanoplatforms loaded with enzymes, since, on one hand, they can be recovered and reused, other improve their catalytic activity increase stability, avoiding processes such as aggregation or autolysis. this review, we evaluate a series key parameters governing enzyme–nanoparticle immobilization phenomena from thermodynamic kinetic point view. We also focus use magnetite nanoparticles (MNPs) multifunctional vectors able anchor summarize most relevant aspects functionalization and, finally, describe some recent applications enzyme–MNP hybrids biocatalysts especial emphasis cancer therapy.