Enzymatic and non-enzymatic functions of the lysyl oxidase family in bone
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چکیده
منابع مشابه
Modulation of lysyl oxidase-like 2 enzymatic activity by an allosteric antibody inhibitor.
In this report, we assessed the steady-state enzymatic activity of lysyl oxidase-like 2 (LOXL2) against the substrates 1,5-diaminopentane (DAP), spermine, and fibrillar type I collagen. We find that both DAP and spermine are capable of activating LOXL2 to the same extent and have similar Michaelis constants (K(m) approximately 1 mm) and catalytic rates (k(cat) approximately 0.02 s(-1)). We also...
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Strong antioxidant activity of Pelargonium graveolens is well known. The question addressed in this study was whether different concentrations of exogenous ascorbic acid (AsA) and iron (Fe) were able to influence antioxidant activity and total phenol content (TPC) of geranium. Thus, three levels of Fe (0, 20 and 40 µM) and three levels of AsA (0, 1 and 2 mM) in nutrient solution were c...
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the etiopathogenesis of alzheimer's disease (ad) is still unclear. however, long-term oxidative stress is believed to be one of the major contributing factors in progression of neuronal degeneration and decline of cognitive function in ad. in order to assess the presence of oxidative stress in ad, we examined the enzymatic activities of the erythrocyte cu-zn superoxide dismutase (cu-zn sod), g...
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Background and Objectives: Cinnamon contains phenolic and non-phenolic bioactive compounds. The aim of this research was investigating the antimicrobial and anti-enzymatic properties of cinnamon (Cinnamomum verum) hydrosol. Materials and Methods: In this laboratory study, chemical composition of cinnamon hydrosol was analyzed by Gas chromatography–mass spectrometry method. Antibacterial effec...
متن کاملEnzymatic and non-enzymatic antioxidants in selected Piper species.
Piper species, commonly used in diet and traditional medicine were assessed for their antioxidant potential. Catalase activity was predominated in Piper longum, followed by Piper cubeba, green pepper, Piper brachystachyum and Piper nigrum. P. nigrum was richest in glutathione peroxidase and glucose-6-phosphate dehydrogenase, green pepper was richest in peroxidase and vitamin C while vitamin E w...
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ژورنال
عنوان ژورنال: Matrix Biology
سال: 2016
ISSN: 0945-053X
DOI: 10.1016/j.matbio.2016.01.001