Enzymatic activities of the GB virus-B RNA-dependent RNA polymerase
نویسندگان
چکیده
منابع مشابه
Enhancement of RNA Interference Effect in P19 EC Cells by an RNA-dependent RNA Polymerase
Background: RNA interference (RNAi) is a phenomenon uses double-stranded RNA (dsRNA) to specifically inhibit gene expression. The non-specific silencing caused by interferon response to dsRNA in mammalian cells limits the potential of utilizing RNAi to study gene function. Duplexes of 21-nucleotide short interfering dsRNA (siRNA) inhibit gene expression by RNAi. In some organisms, siRNA can als...
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background: rna interference (rnai) is a phenomenon uses double-stranded rna (dsrna) to specifically inhibit gene expression. the non-specific silencing caused by interferon response to dsrna in mammalian cells limits the potential of utilizing rnai to study gene function. duplexes of 21-nucleotide short interfering dsrna (sirna) inhibit gene expression by rnai. in some organisms, sirna can als...
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DNA-dependent RNA polymerase of mammalian cells has been described by Weiss,' Huang, M\Iaheshwari, and Bonner,2 Goldberg,3 and Biswas and Abrams.4 The activity of RNA polymerase is enhanced if detergents are added to the incubation medium." I Goldberg3 found that ammonium salts at high ionic concentrations are particularly effective in stimulating the activity of the polymerase. Widnell and Tat...
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ژورنال
عنوان ژورنال: Virology
سال: 2003
ISSN: 0042-6822
DOI: 10.1016/s0042-6822(03)00247-2