Entropy-based analysis of the non-linear relationship between gene expression profiles of amplified and non-amplified RNA
نویسندگان
چکیده
منابع مشابه
Entropy-based analysis of the non-linear relationship between gene expression profiles of amplified and non-amplified RNA.
Two critical issues in microarray-based gene expression profiling with amplified RNA are its reliability and reproducibility compared to the non-amplified RNA. In this study, the non-linear relationship between the two methods was evaluated with the entropy in addition to the linear relationship using correlation coefficients. The correlation coefficients within the amplification method and bet...
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Use of Non-Amplified RNA Samples for Microarray Analysis of Gene Expression
Demand for high quality gene expression data has driven the development of revolutionary microarray technologies. The quality of the data is affected by the performance of the microarray platform as well as how the nucleic acid targets are prepared. The most common method for target nucleic acid preparation includes in vitro transcription amplification of the sample RNA. Although this method re...
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ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2007
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.20.6.905