Enterovirus 71 Neuroimaging: âÂÂThe New Polio of the 21st CenturyâÂÂ
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چکیده
منابع مشابه
Enterovirus 71 Neuroimaging: “The New Polio of the 21st Century”
Enterovirus 71 (EV71) typically causes uncomplicated hand foot and mouth disease in young children. However, a minority of patients may develop neurological complications that include brainstem encephalitis, acute flaccid paralysis, encephalomyelitis, encephalitis and pulmonary oedema. In the wake of near complete global polio eradication, EV71 has emerged as a significant infectious cause of s...
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Enterovirus 71 (EV71) outbreaks occur periodically in the Asia-Pacific region. In 2006, Brunei reported its first major outbreak of EV71 infections, associated with fatalities from neurologic complications. Isolated EV71 strains formed a distinct lineage with low diversity within subgenogroup B5, suggesting recent introduction and rapid spread within Brunei.
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Hand, foot and mouth disease (HFMD) is a common illness of infants and young children <10 years of age. It is characterized by fever, ulcers in the oral cavity, and rashes with blisters that appear on the palm and sole. The most common causal agents of HFMD are coxsackievirus A16 (CV-A16) and human enterovirus 71 (HEV71), but other enteroviruses, including CV-A5 and CV-A10, can also cause it. W...
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In France during 2012, human enterovirus 71 (EV-A71) subgenogroup C4 strains were detected in 4 children hospitalized for neonatal fever or meningitis. Phylogenetic analysis showed novel and independent EV-A71 introductions, presumably from China, and suggested circulation of C4 strains throughout France. This observation emphasizes the need for monitoring EV-A71 infections in Europe.
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Enterovirus 71 (EV71) and coxsackieviruses are the major causative agents of hand, foot, and mouth disease (HFMD) outbreaks worldwide and have a significant socioeconomic impact, particularly in Asia. Formalin-inactivated (FI) EV71 vaccines evaluated in human clinical trials in China, Taiwan, and Singapore were found to be safe and to elicit strong neutralizing antibody responses against EV71 c...
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ژورنال
عنوان ژورنال: Pediatrics & Therapeutics
سال: 2015
ISSN: 2161-0665
DOI: 10.4172/2161-0665.1000i111