منابع مشابه
Enrichment analysis with EpiAnnotator.
Motivation Deciphering relevant biological insights from epigenomic data can be a challenging task. One commonly used approach is to perform enrichment analysis. However, finding, downloading and using the publicly available functional annotations requires time, programming skills and IT infrastructure. Here we describe the online tool EpiAnnotator for performing enrichment analyses on epigenom...
متن کاملPathway Enrichment Analysis with Networks
Detecting associations between an input gene set and annotated gene sets (e.g., pathways) is an important problem in modern molecular biology. In this paper, we propose two algorithms, termed NetPEA and NetPEA', for conducting network-based pathway enrichment analysis. Our algorithms consider not only shared genes but also gene-gene interactions. Both algorithms utilize a protein-protein intera...
متن کاملEnrichment of fish eggs with ascorbic acid
Success in aquaculture depends on the mass production and quality of juveniles. However, many fish species suffered high losses during the early stages of development. Therefore, in order to decrease mortality, produce a large number of healthy larvae is a fundamental issue. On the other hand, one of the micronutrients that can be effective in larvae health is ascorbic acid. During the embryoni...
متن کاملRIP-chip enrichment analysis
MOTIVATION RIP-chip is a high-throughput method to identify mRNAs that are targeted by RNA-binding proteins. The protein of interest is immunoprecipitated, and the identity and relative amount of mRNA associated with it is measured on microarrays. Even if a variety of methods is available to analyse microarray data, e.g. to detect differentially regulated genes, the additional experimental step...
متن کاملKEA: kinase enrichment analysis
MOTIVATION Multivariate experiments applied to mammalian cells often produce lists of proteins/genes altered under treatment versus control conditions. Such lists can be projected onto prior knowledge of kinase-substrate interactions to infer the list of kinases associated with a specific protein list. By computing how the proportion of kinases, associated with a specific list of proteins/genes...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2018
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/bty007