Enlargement of Thalamic Nuclei in Tourette Syndrome
نویسندگان
چکیده
منابع مشابه
Thalamic Deep Brain Stimulation for Tourette Syndrome
L. Ackermansa, I. Neunerb, Y. Temela,c, A. Duitsd,e, J. Kuhnf and V. Visser-Vandewalleg,∗ Department of Neurosurgery, Maastricht University Medical Centre, Maastricht, The Netherlands Department of Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany European Graduate School of Neuroscience (EURON), Faculty of Health, Medicine and Life Science, Maastricht, The Netherlands Depar...
متن کاملInternal pallidal and thalamic stimulation in patients with Tourette syndrome.
BACKGROUND Tourette syndrome (TS) is thought to result from dysfunction of the associative-limbic territories of the basal ganglia, and patients with severe symptoms of TS respond poorly to medication. High-frequency stimulation has recently been applied to patients with TS in open studies using the centromedian-parafascicular complex (CM-Pf) of the thalamus, the internal globus pallidus (GPi),...
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We used [F-18]fallypride PET in six adults with Tourette syndrome and age-matched controls to assess extrastriatal dopamine 2 (D2) receptors. D2 receptor availability was significantly lower in the orbitofrontal cortex, primary motor cortex, anterior cingulate gyrus, mediodorsal nucleus of thalamus, and hippocampus, areas important for motivation and reward, sensory gating, movement, and attent...
متن کاملGlobal network modulation during thalamic stimulation for Tourette syndrome
Background and objectives Deep brain stimulation (DBS) of the thalamus is a promising therapeutic alternative for treating medically refractory Tourette syndrome (TS). However, few human studies have examined its mechanism of action. Therefore, the networks that mediate the therapeutic effects of thalamic DBS remain poorly understood. Methods Five participants diagnosed with severe medically ...
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Gilles de la Tourette syndrome is a childhood-onset syndrome characterized by the presence and persistence of motor and vocal tics. A dysfunction of cortico-striato-pallido-thalamo-cortical networks in this syndrome has been supported by convergent data from neuro-pathological, electrophysiological as well as structural and functional neuroimaging studies. Here, we addressed the question of str...
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ژورنال
عنوان ژورنال: Archives of General Psychiatry
سال: 2010
ISSN: 0003-990X
DOI: 10.1001/archgenpsychiatry.2010.102