Enhanced Transdermal Delivery of Diclofenac Sodium via Conventional Liposomes, Ethosomes, and Transfersomes
نویسندگان
چکیده
منابع مشابه
Enhanced Transdermal Delivery of Diclofenac Sodium via Conventional Liposomes, Ethosomes, and Transfersomes
The aim of this study was to improve the transdermal permeation of Diclofenac sodium, a poorly water-soluble drug, employing conventional liposomes, ethosomes, and transfersomes. The prepared formulations had been characterized for the loaded drug amount and vesicle size. The prepared vesicular systems were incorporated into 1% Carbopol 914 gel, and a survey of in vitro drug release and drug re...
متن کاملEnhanced transdermal bioavailability of testosterone propionate via surfactant-modified ethosomes
The current investigation aimed to evaluate the transdermal potential of novel testosterone propionate (TP) ethosomes and liposomes prepared by surfactant modification. The effect of hexadecyl trimethyl ammonium bromide and cremophor EL-35 on the particle size and zeta potential of the prepared vesicles was investigated. The entrapment efficiency and stability, as well as in vitro and in vivo s...
متن کاملTransdermal Drug Delivery through Carriers: Transfersomes
Delivery of drug through Transdermal route represents a most convenient and novel approach. Transfersomes were found to be more effective as they render controlled release of drug due to depot formation in skin and were more effective in transdermal delivery. Transfersomes are applied to the skin and permeate through the stratum corneum lipid lamellar regions as a result of the hydration and os...
متن کاملTransfersomes: A Novel Vesicular Carrier for Enhanced Transdermal Delivery of Sertraline: Development, Characterization, and Performance Evaluation
The aim of the present study was to investigate transfersomes as a transdermal delivery system for the poorly soluble drug, sertraline, in order to overcome the troubles associated with its oral delivery. Different transfersomal formulations were prepared with non-ionic surfactant (span 80), soya lecithin, and carbopol 940 by the rotary evaporation sonication method. The prepared formulations w...
متن کاملEthosomes: a Novel Nano Vesicular Carrier for Enhanced Dermal, Transdermal and Intracellular Drug Delivery
Ethosomes are ethanolic liposomes, a novel lipid vesicular carrier prepared using phospholipid, ethanol and water. Instead of rupturing the liposomal structure while increasing the ethanol concentration, vesicles superior in delivering the active ingredient into the deeper layers of the skin was obtained, named as ethosomes. In contrast to the liposomes and deformable liposomes, ethosomes have ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BioMed Research International
سال: 2013
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2013/616810