Enhanced mass sensing using torsional and lateral resonances in microcantilevers

Direct torsional actuation of microcantilevers using magnetic excitation

Parametric Resonance in Microcantilevers with Application in Mass Sensing

1.1 Characteristic phase dependance between direct forcing and parametric amplified forcing phase. Plotted is gain vs. phase at resonance for a 2.1 Simulated response of a parametrically resonant system under two driving conditions. The drive signal is shifted by pi-radians. The physical response, displacement is plotted here, is identical as driven by the two signals. Thus, phase shifting the ...

Sensing surface PEGylation with microcantilevers

Polymers are often used to modify surface properties to control interfacial processes. Their sensitivity to solvent conditions and ability to undergo conformational transitions makes polymers attractive in tailoring surface properties with specific functionalities leading to applications in diverse areas ranging from tribology to colloidal stability and medicine. A key example is polyethylene g...

Torsional sensing of small-molecule binding using magnetic tweezers

DNA-binding small molecules are widespread in the cell and heavily used in biological applications. Here, we use magnetic tweezers, which control the force and torque applied to single DNAs, to study three small molecules: ethidium bromide (EtBr), a well-known intercalator; netropsin, a minor-groove binding anti-microbial drug; and topotecan, a clinically used anti-tumor drug. In the low-force ...

The effect of discrete lateral and torsional bracings stiffness on the elastic lateral-torsional buckling of mono-symmetric I beam, under the concentrated moment

When the out-of-plane stiffness of a beam is remarkably lower than the in-plane stiffness, the lateral-torsional buckling occurs. In this study, the behavior of mono-symmetric I-beams with discrete torsional and lateral bracings under the concentrated moment is investigated using the finite element analyses. Then, based on the numerical analyses, equation for the stiffness requirement is propos...