Engineering of citrus to obtain huanglongbing resistance

Huanglongbing (HLB) disease is threatening the sustainability of citriculture in affected regions because its rapid spread and severity symptoms it induces. Herein, we summarise main research findings that can be exploited to develop HLB-resistant cultivars. A major bottleneck has been lack a system for ex vivo cultivation HLB-associated bacteria (CLs) true plant hosts, which precludes evaluation target genes/metabolites reliable plant/pathogen/vector environments. With regard HLB vectors, several biotechnologies have proven laboratory settings effective insect control are presented. Finally, new genotypes resistant CLs or their vectors described, most relevant strategies fighting highlighted.