Engineering biomaterials to control cell function
نویسندگان
چکیده
منابع مشابه
Engineering microenvironments to control stem cell fate and function ∗
2.1. Immobilization of signaling factors as a mechanism to control local concentration . . . . . . . . . . . . . 3 2.2. Sequential factors to program stem cell differentiation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.3. Factors secreted or presented from differentiated cells within the niche . . . . . . . . . . . . . . . . . . . . . . 4 3. Direct cell-cell con...
متن کاملto control cell function
important for the development of new materials for biological applications1. To study cell biology, cells are typically removed from their host organism and cultured on a plastic culture dish – an environment unlike their natural, physiological environment2. Thus, cells tend to lose many of their normal functions and often dedifferentiate for reasons that are not well understood. Recognizing th...
متن کاملEngineering biomaterials for synthetic neural stem cell microenvironments.
Neural stem cells (NSCs) have been isolated from various speciesssuch as mice, rats, and humanssand from numerous regions in the developing and adult nervous systemsincluding the subventricular zone (SVZ), the subgranular zone of the hippocampus, the cortical neuroepithelium, and the spinal cord. In vivo, the NSC is encompassed by a microenvironment or niche that presents it with a repertoire o...
متن کاملStem cell-based tissue engineering with silk biomaterials.
Silks are naturally occurring polymers that have been used clinically as sutures for centuries. When naturally extruded from insects or worms, silk is composed of a filament core protein, termed fibroin, and a glue-like coating consisting of sericin proteins. In recent years, silk fibroin has been increasingly studied for new biomedical applications due to the biocompatibility, slow degradabili...
متن کاملBiomaterials for Cardiac Tissue Engineering
Cardiovascular diseases (CVD) are a leading death cause in developed countries (1 of every 3 deaths in the United States in 2008) [1]. Changes in diet and habits are causing CVD to become major mortality pathologies in developing countries too [2] (they are already responsible for a 30% of the world deaths). This group of diseases constitutes a great burden for the national health systems, cons...
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ژورنال
عنوان ژورنال: Materials Today
سال: 2005
ISSN: 1369-7021
DOI: 10.1016/s1369-7021(05)71222-0