منابع مشابه
Brown adipose tissue: development, metabolism and beyond.
Obesity represents a major risk factor for the development of several of our most common medical conditions, including Type 2 diabetes, dyslipidaemia, non-alcoholic fatty liver, cardiovascular disease and even some cancers. Although increased fat mass is the main feature of obesity, not all fat depots are created equal. Adipocytes found in white adipose tissue contain a single large lipid dropl...
متن کاملHormonal Control of Brown-Adipose-Tissue Metabolism
Ho, R. J. & Sutherland, E. W. (1972) J. Biol. Chem. 246, 6822-6827 Lernonnier, D., Winand. J., Furnelle, J. & Christophe, J . (1971) Diaherologia7, 328-333 Wieland, 0. ( I 957) Biochem. Z. 329, 3 13-3 I9 Winand, J. & Christophe, J. (1976) Arch. Int. P/7ysiol. Biochim. 84, 207-208 Winand, J., Furnelle, J. & Christophe, J. (1967) Bull. Soc. Chim. Biol. 49, 1845-1862 Winand, J., Furnelle, J., Wodo...
متن کاملCIDE Family-Mediated Unique Lipid Droplet Morphology in White Adipose Tissue and Brown Adipose Tissue Determines the Adipocyte Energy Metabolism
White adipose tissue (WAT) stores energy as triacylglycerol in preparation for fasting state. In contrast, brown adipose tissue (BAT) consumes energy and produces heat in a cold environment. One of the major differences between these two adipose tissues is the morphology of the intracellular lipid droplet (LD), which is large and unilocular in WAT and small and multilocular in BAT. Although the...
متن کاملBrown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans.
Brown adipose tissue (BAT) is vital for proper thermogenesis during cold exposure in rodents, but until recently its presence in adult humans and its contribution to human metabolism were thought to be minimal or insignificant. Recent studies using PET with 18F-fluorodeoxyglucose (18FDG) have shown the presence of BAT in adult humans. However, whether BAT contributes to cold-induced nonshiverin...
متن کاملBrown adipose tissue
Obesity is currently a global pandemic, and is associated with increased mortality and co-morbidities including many metabolic diseases. Obesity is characterized by an increase in adipose mass due to increased energy intake, decreased energy expenditure, or both. While white adipose tissue is specialized for energy storage, brown adipose tissue has a high concentration of mitochondria and uniqu...
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ژورنال
عنوان ژورنال: The FEBS Journal
سال: 2021
ISSN: 1742-464X,1742-4658
DOI: 10.1111/febs.16015