Endotoxemia in organ donors: graft function following liver transplantation
نویسندگان
چکیده
منابع مشابه
Graft calcifications and dysfunction following liver transplantation
BACKGROUND The molecular events, following ischemia and reperfusion (I/R) of the liver during transplantation are largely unknown. There is evidence that apoptotic and necrotic events may take place, and occasionally result in primary graft dysfunction. We herein report two cases, where significant I/R injury correlated with the development of liver calcification and primary liver dysfunction. ...
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Background and Objectives: The main challenge in liver transplantation is shortage of donor organs, and using living donor live transplantation (LDLT) has been considered as a new strategy. This study aimed to explore the concept of liver transplantation in living donors’ experiences after donating. Materials and Methods: A qualitative study with qualitative descriptive approach was co...
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Preserving donor organs in optimal condition is a prerequisite for successful transplantation. The donor organ is subjected to a multitude of stresses. In this review, we will discuss the consequences of brain death on donor organs. The effects of an extended ischaemic period followed by the reperfusion necessary for the harvest, storage and implantation of transplant organs will be evaluated. ...
متن کاملEndotoxemia and human liver transplantation.
Ninety liver transplantations were performed in 81 patients. Plasma endotoxin was measured preoperatively, at the end of the anhepatic phase, and on postoperative days 1, 3, and 7. The presence of high endotoxin levels preoperatively and at the end of the anhepatic period was associated with graft failure and a high mortality. Patients with primary nonfunction of their transplants typically had...
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Long-term outcomes in solid organ transplantation are constrained by the development of donor-specific alloantibodies (DSA) against human leukocyte antigen (HLA) and other targets, which elicit antibody-mediated rejection (ABMR). However, antibody-mediated graft injury represents a broad continuum, from extensive complement activation and tissue damage compromising the function of the transplan...
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ژورنال
عنوان ژورنال: Transplant International
سال: 2000
ISSN: 0934-0874
DOI: 10.1111/j.1432-2277.2000.tb02039.x