Endothelial Dysfunction in Essential Hypertension
نویسندگان
چکیده
منابع مشابه
Endothelial dysfunction in salt-sensitive essential hypertension.
The aim of this study was to evaluate endothelium-dependent and -independent vasodilation, as well as endothelium biochemical markers, in a group of essential hypertensive patients classified on the basis of salt sensitivity. Changes in forearm blood flow in response to acetylcholine, sodium nitroprusside, and N(G)-monomethyl-L-arginine (L-NMMA) infusion were determined by means of strain-gauge...
متن کاملAsymmetric dimethylarginine, L-arginine, and endothelial dysfunction in essential hypertension.
OBJECTIVES We investigated the relationship between ADMA plasma levels and endothelium-dependent vasodilation in 36 never-treated essential hypertensives and in 8 normotensive healthy subjects. BACKGROUND It has been demonstrated that endothelium-dependent vasodilatation is impaired in essential hypertension. The potential contribution of asymmetric dimethylarginine (ADMA) to endothelial dysf...
متن کاملEndothelial dysfunction and mild renal insufficiency in essential hypertension.
BACKGROUND Mild to moderate renal insufficiency in individuals with essential hypertension is currently considered the expression of a renal microvasculopathy characterized by preglomerular arteriolar involvement and tubulo-interstitial changes. Whether endothelial dysfunction plays a role in this alteration is still undefined. METHODS AND RESULTS We investigated the relationship between endo...
متن کاملRole of endothelial cell dysfunction in essential hypertension.
BACKGROUND Hypertension is associated with functional and morphological alterations of the endothelium, which disturbs delicate balance of endothelium-derived factors resulting in endothelial dysfunction. The endothelial dysfunction could then facilitate the maintenance of elevated peripheral resistance, which would favor the occurrence of atherosclerosis. AIMS AND OBJECTIVES The aim of the p...
متن کاملUric acid and endothelial dysfunction in essential hypertension.
Recent epidemiologic and experimental evidence suggests that serum uric acid (UA) is an independent risk factor for cardiovascular and renal diseases. However, endothelial dysfunction is an early predictor of cardiovascular events, particularly in hypertensive patients. For assessment of the association between UA and endothelial function, 217 (108 men, 109 women; aged 48.0 +/- 10.6 yr) white n...
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ژورنال
عنوان ژورنال: Clinical Cardiology
سال: 1997
ISSN: 0160-9289,1932-8737
DOI: 10.1002/j.1932-8737.1997.tb00009.x