Endoplasmic reticulum microenvironment and conserved histidines govern ELOVL4 fatty acid elongase activity
نویسندگان
چکیده
منابع مشابه
Cancer Microenvironment and Endoplasmic Reticulum Stress Response
Different stressful conditions such as hypoxia, nutrient deprivation, pH changes, or reduced vascularization, potentially able to act as growth-limiting factors for tumor cells, activate the unfolded protein response (UPR). UPR is therefore involved in tumor growth and adaptation to severe environments and is generally cytoprotective in cancer. The present review describes the molecular mechani...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 2014
ISSN: 0022-2275
DOI: 10.1194/jlr.m045443