منابع مشابه
Endoderm specification
In this chapter I focus on the emergence of endoderm, the origin of these cells and their organization in space. I also discuss the molecular events that lead to endoderm formation and how endoderm can be molecularly defined. Although the molecular control of endoderm formation has initially been deciphered using Xenopus, Zebrafish, sea urchin and several other species many molecular switches h...
متن کاملSpecification of pharyngeal endoderm
For more than a century, vertebrate taste buds have been singled out as the prime example of neural induction of sensory organs during development. This view has held that late in embryogenesis, sensory nerve fibers contacted the oral and pharyngeal epithelia, and induced a subset of epithelial cells to give rise to multicellular taste buds (Guth, 1957; Hosley et al., 1987; Torrey, 1940). The i...
متن کاملSpecification of endoderm in the sea urchin embryo
Expression of the endoderm specific gene Endo16, was used to monitor endoderm specification in developmentally arrested and in dissociated embryos. beta-APN treatment halts gastrulation, however, in two species of sea urchins Endo16 mRNA is still expressed, suggesting that specification of the endodermal lineage has taken place in these developmentally arrested embryos. Endo16 mRNA is not expre...
متن کاملGenetic redundancy in endoderm specification within the genus Caenorhabditis.
Specification of the endoderm precursor, the E cell, in Caenorhabditis elegans requires a genomic region called the Endoderm Determining Region (EDR). We showed previously that end-1, a gene within the EDR encoding a GATA-type transcription factor, restores endoderm specification to embryos deleted for the EDR and obtained evidence for genetic redundancy in this process. Here, we report molecul...
متن کاملPrimitive endoderm differentiation: from specification to epithelium formation.
In amniotes, primitive endoderm (PrE) plays important roles not only for nutrient support but also as an inductive tissue required for embryo patterning. PrE is an epithelial monolayer that is visible shortly before embryo implantation and is one of the first three cell lineages produced by the embryo. We review here the molecular mechanisms that have been uncovered during the past 10 years on ...
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ژورنال
عنوان ژورنال: StemBook
سال: 2008
ISSN: 1940-3429
DOI: 10.3824/stembook.1.30.1