Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi
نویسندگان
چکیده
منابع مشابه
Molecular and microscopic detection of Theileria equi and Babesia caballi in horses in Kurdestan Province, Iran
Equine piroplasmosis is a tick-borne disease caused by intra-erythrocyte protozoa, Theileria equi and Babesia caballi. The present study aimed to detect piroplasm infection in horses in Kurdestan Province, Iran, through molecular and microscopic approaches.n this study, 186 blood samples were randomly collected from horses of five regions of Kurdestan Province. The Tbs-S/Tbs-A primer set was us...
متن کاملDifferential Expression of Three Members of the Multidomain Adhesion CCp Family in Babesia bigemina, Babesia bovis and Theileria equi
Members of the CCp protein family have been previously described to be expressed on gametocytes of apicomplexan Plasmodium parasites. Knocking out Plasmodium CCp genes blocks the development of the parasite in the mosquito vector, making the CCp proteins potential targets for the development of a transmission-blocking vaccine. Apicomplexans Babesia bovis and Babesia bigemina are the causative a...
متن کاملSeroprevalence of Theileria equi and Babesia caballi infection in Turkoman breed horses in Iran
Equine babesiosis is a hemoprotozoan tickborne disease with worldwide distribution and caused by Theileria equi and Babesia caballi. This study was conducted to determine the seroprevalence of T. equi and B. caballi infection in Turkoman breed horses in North Khorasan Province of Iran. Blood samples were collected from 100 apparently healthy horses and examined by microscopy and indirect immuno...
متن کاملEstimation of the transmission dynamics of Theileria equi and Babesia caballi in horses.
For the evaluation of the epidemiology of Theileria equi and Babesia caballi in a herd of 510 horses in SW Mongolia, several mathematical models of the transmission dynamics were constructed. Because the field data contain information on the presence of the parasite (determined by PCR) and the presence of antibodies (determined by IFAT), the models cater for maternal protection with antibodies,...
متن کاملClinical investigation on Theileria equi and Babesia caballi infections in Italian donkeys
BACKGROUND Interest in the welfare and diseases of donkeys is constantly increasing in several countries. Despite this, clinical research into donkeys needs to be in continual development since they show different reactions compared to horses in many conditions, including infectious diseases, and need specific clinical and therapeutic approaches. No reports are currently available on clinical a...
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ژورنال
عنوان ژورنال: Parasites & Vectors
سال: 2020
ISSN: 1756-3305
DOI: 10.1186/s13071-020-04487-3