Encephalitis Lethargica: An Autoimmune Disease

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چکیده

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Encephalitis Lethargica

There is an cspccial fascination to the clinician attaching to a disorder which presents no single distinctive feature, which may simulate, or be simulated by, a large number of other affections, and in the recognition of which cytological, bacteriological, and chemical procedures have hitherto failed to afford any positive assistance. I may remind you that in the spring of 1917 von Economo5 di...

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Encephalitis Lethargica

Encephalitis lethargica (EL) was named and described by Von Economo in 1916, and further detailed in a monograph in 1931 [1] following the pandemic of 1919 to 1926, but for many years was regarded as a phenomenon of the past. In recent years there has been a recurrence of interest in the disease, concerning aetiology and links with post encephalitic parkinsonism. Oliver Sacks described awakenin...

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Three Cases of Encephalitis Lethargica

was somewhat prevalent in the adjoiningvillages.) Both had one or two watery motions each and both vomited twice. They had nausea also and were complaining of giddiness. This had occurred in the afternoon. Yet the children were moving about till the evening. Their mother got alarmed at their increasing giddiness and nausea, and sent for their father. He, being a doctor, found them somewhat unea...

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Encephalitis Lethargica: A Clinical Lecture

UENTLEMivN,?1 present to you here two cubes of Encephalitis Lethargica, recorded to-day for the first time from the Andaman Isles. This disease as a definite entity first attracted the attention of medical men in the springy of 1917, when Von Economa drew attention to "A New Disease" in and around Vienna which was assuming a mild epidemic character. This disease was boomed in the lay press as "...

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Evidence for an enterovirus as the cause of encephalitis lethargica

BACKGROUND The epidemic of encephalitis lethargica (EL), called classical EL, was rampant throughout the world during 1917-1926, affecting half a million persons. The acute phase was lethal for many victims. Post-encephalitic parkinsonism (PEP) affected patients for decades. Our purpose was to investigate the cause of classical EL by studying the few available brain specimens. Cases of PEP and ...

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ژورنال

عنوان ژورنال: Pediatric Neurology Briefs

سال: 2004

ISSN: 2166-6482,1043-3155

DOI: 10.15844/pedneurbriefs-18-1-1