Encapsulation of hemoglobin in a bicontinuous cubic phase lipid
نویسندگان
چکیده
منابع مشابه
Electrostatic swelling of bicontinuous cubic lipid phases.
Lipid bicontinuous cubic phases have attracted enormous interest as bio-compatible scaffolds for use in a wide range of applications including membrane protein crystallisation, drug delivery and biosensing. One of the major bottlenecks that has hindered exploitation of these structures is an inability to create targeted highly swollen bicontinuous cubic structures with large and tunable pore si...
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We investigate the stability of seven inverse bicontinuous cubic phases [ G, D, P, C(P), S, I-WP, F-RD] in lipid-water mixtures based on a curvature model of membranes. Lipid monolayers are described by parallel surfaces to triply periodic minimal surfaces. The phase behavior is determined by the distribution of the Gaussian curvature on the minimal surface and the porosity of each structure. O...
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I studied the transformation between inverse bicontinuous cubic phases (QII) from diamond (QII(D)) to primitive (QII(P)) in a single-crystal region of monoolein. X-ray diffraction data reveal that the crystallographic orientation of QII(P) rotates 55° around the [01̅1] axis from QII(D). This indicates that one direction of the four-branched water channels in the QII(D) phase is preserved in the ...
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Bulk and dispersed cubic liquid crystalline phases (cubosomes), present in the body and in living cell membranes, are believed to play an essential role in biological phenomena. Moreover, their biocompatibility is attractive for nutrient or drug delivery system applications. Here the three-dimensional organization of dispersed cubic lipid self-assembled phases is fully revealed by cryo-electron...
متن کاملX-ray scattering by bicontinuous cubic phases
-Ia3d bicontinuous cubic phases are interpreted as constituted of a fluid film of constant thickness supponed by the gyroid minimal surface. We first compute the gyroid structure factor. Then we decorate the surface by the film. We compute the diffracted intensities and compare to X-ray intensities measured in some lipid
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 1996
ISSN: 0005-2736
DOI: 10.1016/s0005-2736(96)00169-1