Encapsulating Streptomycin within a Small 40-mer RNA

RNA Isolation (Small RNA Extraction). Fatemeh Mehrpooyan*

Encapsulating zinc(II) within a hydrophobic cavity.

A new macrobicyclic ligand has been prepared, and it is shown to bind Zn(2+) on the inside. The ligand consists of a triamido(amine) motif to coordinate the metal ion and a narrow, hydrophobic channel above the metal binding site.

Small interfering RNA; principles, applications and challenges--

Gene silencing using RNAi (RNA interference), has recently been used as a successful laboratory technique in determining the function and control of gene expression and provides a wide range of applications in molecular biology and gene therapy. RNAi is a method of suppressing gene expression. In this direction, a single-stranded RNA molecule of about 21–23 nucleotides, called siRNA (small inte...

Wrapper Facade A Structural Pattern for Encapsulating Functions within Classes

This paper describes the Wrapper Facade pattern. The intent of this pattern is to encapsulate low-level functions and data structures with object-oriented (OO) class interfaces. Common examples of the Wrapper Facade pattern are class libraries like MFC, ACE, and AWT that encapsulate native OS C APIs, such as sockets, pthreads, or GUI functions. Programming directly to native OS C APIs makes net...

Experience with Unusually Small Doses of Streptomycin