Enantioselective synthesis of (-)-(5R,6S)-6-acetoxyhexadecan-5-olide via tandem α-aminooxylation-Henry reaction
نویسندگان
چکیده
منابع مشابه
Enantioselective organocatalyzed Henry reaction with fluoromethyl ketones.
Remarkable generality in scope of new C9-benzoylcupreines bearing electron-withdrawing substituents for the nitroaldol condensation with fluoromethyl ketones is presented. Both tri- and difluoromethyl ketones provided excellent levels of stereoinduction (ee 76-99%) under mild reaction conditions and low loading of catalyst (1-5 mol%).
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2018
ISSN: 1551-7012
DOI: 10.24820/ark.5550190.p010.635