Enamel Defects Reflect Perinatal Exposure to Bisphenol A
نویسندگان
چکیده
منابع مشابه
Perinatal exposure to bisphenol a increases adult mammary gland progesterone response and cell number.
Bisphenol A [BPA, 2,2,-bis (hydroxyphenyl) propane] is one of the highest-volume chemicals produced worldwide. It is detected in body fluids of more than 90% of the human population. Originally synthesized as an estrogenic compound, it is currently utilized to manufacture food and beverage containers resulting in uptake with food and drinks. There is concern that exposure to low doses of BPA, d...
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Bisphenol A (BPA) is a widespread endocrine-disrupting chemical used as the building block for polycarbonate plastics. Epidemiological evidence has correlated BPA exposure with higher risk of heart disease and type 2 diabetes. However, it remains unknown whether there are critical windows of susceptibility to BPA exposure on the development of dysglycemia. This study was an attempt to investiga...
متن کاملPerinatal exposure to low-dose bisphenol A impairs spatial learning and memory in male rats.
Bisphenol A (BPA) is an estrogenic endocrine disruptor used for producing polycarbonate plastics and epoxy resins. This study investigated the effects of perinatal BPA exposure on learning and memory, general activity, and emotionality in male Sprague Dawley rats using a battery of behavioral tests, including an appetite-motivated maze test (MAZE test) used to assess spatial learning and memory...
متن کاملPerinatal Exposure to Bisphenol A Alters Early Adipogenesis in the Rat
BACKGROUND The causes of the current obesity pandemic have not been fully elucidated. Implication of environmental endocrine disruptors such as bisphenol A (BPA) on adipose tissue development has been poorly investigated. OBJECTIVES The aim of the present study was to evaluate the effects of perinatal exposure to BPA on early adipose storage at weaning. METHODS Pregnant Sprague-Dawley rats ...
متن کاملEffects of perinatal exposure to bisphenol A on sociosexual behavior of female and male rats.
Perinatal action of estrogens or aromatizable steroids at the central nervous system level is responsible for brain sexual differentiation. Through early contact with the central nervous system, the estrogenic compound bisphenol A (BPA) could alter the processes affecting sociosexual behavior. To test this hypothesis, we studied agonistic and sexual behavior of adult female and male rats whose ...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2013
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2013.04.004