Enabling stem cell therapies through synthetic stem cell–niche engineering

P11: From Well to Bed: Stem Cell Therapies for Neurotrauma

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Stem cell niche engineering through droplet microfluidics.

Stem cells reside in complex niches in which their behaviour is tightly regulated by various biochemical and biophysical signals. In order to unveil some of the crucial stem cell-niche interactions and expedite the implementation of stem cells in clinical and pharmaceutical applications, in vitro methodologies are being developed to reconstruct key features of stem cell niches. Recently, drople...

Engineering biomaterials for synthetic neural stem cell microenvironments.

Neural stem cells (NSCs) have been isolated from various speciesssuch as mice, rats, and humanssand from numerous regions in the developing and adult nervous systemsincluding the subventricular zone (SVZ), the subgranular zone of the hippocampus, the cortical neuroepithelium, and the spinal cord. In vivo, the NSC is encompassed by a microenvironment or niche that presents it with a repertoire o...

Advances in Stem Cell Therapies

Stem Cell Therapies on Pancreatitis