Emerging Roles of miRNAs in Brain Development and Perinatal Brain Injury
نویسندگان
چکیده
منابع مشابه
Emerging Roles for the Immune System in Traumatic Brain Injury
Traumatic brain injury (TBI) affects an ever-growing population of all ages with long-term consequences on health and cognition. Many of the issues that TBI patients face are thought to be mediated by the immune system. Primary brain damage that occurs at the time of injury can be exacerbated and prolonged for months or even years by chronic inflammatory processes, which can ultimately lead to ...
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The guest editors of this journal are pleased to introduce this special issue on the mechanisms of perinatal brain injury. The purpose of this issue is to highlight recent developments toward our understanding of both grey and white matter injury in the perinatal brain. Over the last decade, there has been significant advancement in our understanding of the mechanisms underlying this injury. Th...
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Biological sex and sex-defining steroids are strikingly under-rated as modulators of cerebral ischemic cell death. In adults, male sex has been long identified as a risk factor for clinical stroke, yet the biology behind this fact remains veiled. We know that overall stroke incidence is lower in women than in men, across widely varying ethnic and cultural backgrounds.1 Newer glimpses into this ...
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Introduction: Arterial hypertension is one of the causes of stroke, and as one of the vasculotoxic conditions intensifies ischemic stroke complications. The aim of the present study was to analyze the effects of short-term cerebral hypertension on ischemia/reperfusion injury and pathogenesis of ischemic stroke. Methods: The experiments were performed on three groups of rats (N=36) Sham, cont...
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A growing body of evidence demonstrates that susceptibility and progression of both acute and chronic central nervous system disease in the newborn is closely associated with an innate immune response that can manifest from either direct infection and/or infection-triggered damage. A common feature of many of these diseases is the systemic exposure of the neonate to bacterial infections that el...
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ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2019
ISSN: 1664-042X
DOI: 10.3389/fphys.2019.00227