Emerging Patterns in Antimicrobial Susceptibility Profiles of Pseudomonas SPP- Hospital Based Study

Background: There is an emerging trend of pseudomonas infections in immune-compromised patients, specifically hospital settings. The flagship member this family Pseudomonas aeruginosa, which a major infectious agent. This study assessed the distribution and susceptibility patterns species isolated from various specimens as part surveillance program, order to devise antibiograms. Aim: To determine frequency & antimicrobial sensitivities tertiary care Lahore. Study design: Retrospective, descriptive, cross sectional Place duration study: Conducted Lahore, January 2021 2022. Methods: Thirty two isolates different clinical were microbiology section during period 13 months. MacConkey blood agar utilized for culturing organisms. Gram staining, oxidase, catalase testwere phenotypic characterization. Antibiotic testing against anti-pseudomonal drugs was performed according Clinical Laboratory Standards Institute guidelines (CLSI) 2021. Results: inference drawn at end that, out thirty received pus most common specimen (46.8%), followed by 18.75% urine specimens. 62.5% obtained male patients. affected age group 40-60 years, 1-20 years. sensitive options turned be Imipenem (65.6%) Pipericillintazobactam (62.5%), 59.3% sensitivity Amikacin. least Aztreonam (15.6%) Ticarcillin clavulanic acid (25%). In 18% cultures, fosfomycin 83.3%, whereas nitrofurantoin 50% sensitive. Conclusions: steadily rising resistance againstavailable antibiotics optionsnecessitates their use inlife-threatening acquiredinfections. Keywords: Peudomonas, Flouroquinolones, Carbapenem