Ellagic acid facilitates indomethacin-induced gastric ulcer healing via COX-2 up-regulation

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Ellagic acid facilitates indomethacin-induced gastric ulcer healing via COX-2 up-regulation.

The mechanism of indomethacin-induced gastric ulcer healing by ellagic acid (EA) in experimental mice model is described in our study. Ulcer index (UI) and myeloperoxidase (MPO) activity of the stomach tissues showed maximum ulceration on the third day after indomethacin (18 mg/kg, single dose) administration. Preliminary observation of UI and MPO activity suggests that EA possesses ulcer-heali...

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Sitagliptin Impairs Healing of Experimentally Induced Gastric Ulcers via Inhibition of Inos and Cox-2 Expression

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ژورنال

عنوان ژورنال: Acta Biochimica et Biophysica Sinica

سال: 2012

ISSN: 1672-9145,1745-7270

DOI: 10.1093/abbs/gms034