Eligibility, compliance and persistence of extended adjuvant endocrine therapy for breast cancer

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Selecting adjuvant endocrine therapy for breast cancer.

This year alone, more than 215,000 women in the United States will be diagnosed with, and over 40,000 will die from, invasive breast cancer. Recently, mortality from female breast cancer has declined despite an increase in its incidence. This decline corresponds with improved screening for prompt tumor detection, and advances in the treatment of early disease. Of these, endocrine therapy has pl...

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Adjuvant endocrine therapy for breast cancer.

Endocrine therapy is a critical part of adjuvant therapy in women with hormone receptor-positive breast cancer, and has been shown to reduce the risk of recurrence and death from breast cancer. For decades, 5 years of tamoxifen has been the standard treatment. For premenopausal women, it remains so, and we await the results of ongoing trials to define the role of ovarian suppression or ablation...

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Current status of adjuvant endocrine therapy for breast cancer.

Adjuvant endocrine therapy is a vitally important modality for treatment of women with resected hormone-sensitive breast cancer as indicated by the presence of estrogen and/or progesterone receptors in the tumor. It is not recommended in those patients whose tumors lack these hormone receptors. Tamoxifen for 5 years has been shown to reduce the risk of recurrence and death irrespective of menop...

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Current Status of Adjuvant Endocrine Therapy for Breast Cancer

Adjuvant endocrine therapy is a vitally important modality for treatment of women with resected hormonesensitive breast cancer as indicated by the presence of estrogen and/or progesterone receptors in the tumor. It is not recommended in those patients whose tumors lack these hormone receptors. Tamoxifen for 5 years has been shown to reduce the risk of recurrence and death irrespective of menopa...

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Adjuvant endocrine therapy for postmenopausal women with early breast cancer.

Results from multiple clinical trials involving aromatase inhibitors have added to the knowledge base relating to endocrine therapy of postmenopausal women with hormone receptor-positive early breast cancer. In the extended adjuvant setting, data from the Austrian Breast and Colorectal Cancer Study Group 6a trial showed an advantage for anastrozole following 5 years of tamoxifen treatment, cons...

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ژورنال

عنوان ژورنال: Acta Oncologica

سال: 2011

ISSN: 0284-186X,1651-226X

DOI: 10.3109/0284186x.2011.619567