Elements of (201) Penelope

Distribution and phylogeny of Penelope-like elements in eukaryotes.

Penelope-like elements (PLEs) are a relatively little studied class of eukaryotic retroelements, distinguished by the presence of the GIY-YIG endonuclease domain, the ability of some representatives to retain introns, and the similarity of PLE-encoded reverse transcriptases to telomerases. Although these retrotransposons are abundant in many animal genomes, the reverse transcriptase moiety can ...

Introduction Penelope Rush

This book is a collection of new essays around the broad central theme of the nature of logic, or the question: ‘what is logic?’ It is a book about logic and philosophy equally. What makes it unusual as a book about logic is that its central focus is on metaphysical rather than epistemological or methodological concerns. By comparison, the question of the metaphysical status of mathematics and ...

What happens when Penelope comes?

Transposable elements (TEs) are ubiquitous residents in eukaryotic genomes. They can cause dramatic changes in gene expression and lead to gross rearrangements of chromosome structure, providing the basis for rapid evolution. The virilis species group of Drosophila contains certain species that can be crossed under experimental conditions and their phylogeny is thoroughly investigated. We have ...

air-kerma standards using PENELOPE

Molecular dissection of Penelope transposable element regulatory machinery

Penelope-like elements (PLEs) represent a new class of retroelements identified in more than 80 species belonging to at least 10 animal phyla. Penelope isolated from Drosophila virilis is the only known transpositionally active representative of this class. Although the size and structure of the Penelope major transcript has been previously described in both D. virilis and D. melanogaster trans...