ELEGTROENCEPHALOGRAPHIC STUDIES ON MORPHINE DEPENDENCE IN RAT
نویسندگان
چکیده
منابع مشابه
Morphine tolerance and dependence in the rat intestine in vivo.
There has been no previous demonstration of opioid tolerance and dependence with respect to the propulsive and contractile activities of the gut in vivo. In the experiments described herein, morphine was administered continuously (1 mg/kg/hr s.c., 72 hr) and/or by bolus injection (2 mg/kg) and intestinal motility and transit were evaluated in unanesthetized rats. Tolerance in intestinal motilit...
متن کاملFatal dependence on kaolin and morphine mixture.
A patient is described who had a long history of abuse of kaolin and morphine mixture which ultimately proved fatal.
متن کاملEffects of morphine dependence and withdrawal on levels of neurosteroids in rat brain.
AIM To investigate the effects of morphine dependence and withdrawal on the concentrations of neurosteroids in rat brain. METHODS A method of simultaneous quantification of neurosteroids by gas chromatography-mass spectrometry (GC-MS) had been established. RESULTS The chronic morphine administration (ip) resulted in a marked decrease in the brain concentrations of pregnenolone (PREG), proge...
متن کاملEffects of Morphine Dependency on Bone Healing in Rat
Bone fractures usually happen during car accident and sport trauma. Different factors influence bone healing such as malnutrition and smoking. Apart from addiction which is an important individual, social, and cultural problems morphine has several effects on body physiology and immune system .This study is performed to assess the effect of morphine dependency on bone healing and has not been r...
متن کاملEffects of Morphine Dependency on Intervertebral Disc in the Rat
Background: A large proportion of patients presenting with lumbar disc disease are opium addicts in our region. It was, therefore, hypothesized that morphine might affect the intervertebral disc. We investigated the histological findings of morphine dependency on intervertebral discs in rat. Methods: Forty NMRI adult male rats (230-250 g) placed on ordinary diet and received aqueous solution of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1969
ISSN: 0021-5198
DOI: 10.1254/jjp.19.174