Electronic fingerprinting of RNA

Electronic fingerprinting of RNA.

Software has been developed to assist RNA fingerprinting analysis. One program generates, from a DNA sequence data file, the oligonucleotides resulting from digestion of an RNA transcript labeled with any specified nucleotide(s). Oligonucleotides are sorted according to their position on the fingerprint. Expected molar yields and products of secondary redigestion are also indicated. A second pr...

RNA fingerprinting by molecular indexing.

Class IIS restriction enzymes, a subgroup of class II, cleave DNA at a precise location outside their recognition sites, and produce overhangs of unknown sequences (1). Molecular indexing is a series of techniques designed to characterize DNA fragments by these unknown sequences (2–4). I applied this principle for description of the total mRNA population using a 3′ end cDNA fragment generated b...

Physico-chemical fingerprinting of RNA genes

We advance here a novel concept for characterizing different classes of RNA genes on the basis of physico-chemical properties of DNA sequences. As knowledge-based approaches could yield unsatisfactory outcomes due to limitations of training on available experimental data sets, alternative approaches that utilize properties intrinsic to DNA are needed to supplement training based methods and to ...

Fingerprinting Electronic Molecular Complexes in Liquid

Predicting the electronic framework of an organic molecule under practical conditions is essential if the molecules are to be wired in a realistic circuit. This demands a clear description of the molecular energy levels and dynamics as it adapts to the feedback from its evolving chemical environment and the surface topology. Here, we address this issue by monitoring in real-time the structural ...

Anonymous Fingerprinting of electronic information with automatic identification of redistributors