Electroneurography abnormality in Parkinson’s disease: a potential biomarker to help diagnosis

Parkinson’s disease (PD) is a common neurodegenerative disease, pathologically characterized by the progressive degeneration of dopaminergic neurons in substantia nigra. Although various biomarkers and imaging criteria for PD have been established, objective reliable evaluation methods are still lacking. Electroneurography, as an measurement evoked compound muscle action potentials, used to assess integrity peripheral nerve important diagnosis differential with neuromuscular injury. Moreover, it provides references quantification motor function PD. Here, we summarize recent advances clinical research electroneurography PD, including conduction velocity, needle electromyography, surface motion unit number estimation. The potential values also involved.