Efficient Target-Selected Mutagenesis in Zebrafish
نویسندگان
چکیده
منابع مشابه
Efficient target-selected mutagenesis in Caenorhabditis elegans: toward a knockout for every gene.
Reverse genetic or gene-driven knockout approaches have contributed significantly to the success of model organisms for fundamental and biomedical research. Although various technologies are available for C. elegans, none of them scale very well for genome-wide application. To address this, we implemented a target-selected knockout approach that is based on random chemical mutagenesis and detec...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2003
ISSN: 1088-9051
DOI: 10.1101/gr.1725103