Efficient gamma-aminobutyric acid bioconversion by engineered Escherichia coli
نویسندگان
چکیده
منابع مشابه
Effect of protein and lactulose on the production of gamma-aminobutyric acid by faecal Escherichia coli.
The value of lactulose treatment in hepatic encephalopathy is widely recognised but its mode of action remains controversial. Much evidence supports a role for gamma-aminobutyric acid in hepatic encephalopathy, and lactulose could alter its bacterial production in the gut. Using the rat synaptic membrane assay and gas chromatography mass spectrometry, the production of gamma-aminobutyric acid b...
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Polylactic acid (PLA) is one of the promising biodegradable polymers, which has been produced in a rather complicated two-step process by first producing lactic acid by fermentation followed by ring opening polymerization of lactide, a cyclic dimer of lactic acid. Recently, we reported the production of PLA and its copolymers by direct fermentation of metabolically engineered Escherichia coli e...
متن کاملEfficient synthesis of L-lactic acid from glycerol by metabolically engineered Escherichia coli
BACKGROUND Due to its abundance and low-price, glycerol has become an attractive carbon source for the industrial production of value-added fuels and chemicals. This work reports the engineering of E. coli for the efficient conversion of glycerol into L-lactic acid (L-lactate). RESULTS Escherichia coli strains have previously been metabolically engineered for the microaerobic production of D-...
متن کاملGamma-Aminobutyric Acid (GABA) Monograpy
Introduction Gamma-aminobutyric acid (GABA) is a major neuro transmitter widely distributed throughout the central nervous system (CNS). Because too much excitation can lead to irritability, restlessness, insomnia, seizures, and movement disorders, it must be balanced with inhibition. GABA – the most important inhibitory neurotransmitter in the brain – provides this inhibition, acting like a “b...
متن کاملdetermination of gamma - aminobutyric acid by high-performance liquid chromatography
gamma-aminobutyric acid is the main inhibitory amino acid neurotransmitter in several areas of the brain. measurement of gamma-aminobutyric acid in the brain will help elucidate its metabolic rote and diagnostic value. the liquid chromatography (lc) system consisted of a delivery pump. male rats (150-250g) were used in this study. the brain was rapidly removed from decapitated animals. trie chr...
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ژورنال
عنوان ژورنال: Biotechnology & Biotechnological Equipment
سال: 2018
ISSN: 1310-2818,1314-3530
DOI: 10.1080/13102818.2018.1446765