Efficient and stereoselective synthesis of sugar fused pyrano[3,2-<i>c</i>]pyranones as anticancer agents
نویسندگان
چکیده
A highly stereoselective, efficient and facile route was achieved for the synthesis of novel biochemically potent sugar fused pyrano[3,2- c ]pyranone derivatives starting from inexpensive, naturally occurring d -galactose -glucose.
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چکیده ندارد.
Fused Thiopyrano[2,3-d]thiazole Derivatives as Potential Anticancer Agents
rel-(5aR,11bR)-3,5a,6,11b-tetrahydro-2H,5H-chromeno[4',3':4,5]thiopyrano[2,3-d][1,3]thiazol-2-ones formed by the stereoselective Knoevenagel-hetero-Diels-Alder reaction were functionalized at the nitrogen in position 3 via reactions of alkylation, cyanoethylation, and acylation. The synthesized compounds were evaluated for their anticancer activity in NCI60 cell lines. Among the tested compound...
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ژورنال
عنوان ژورنال: RSC Advances
سال: 2023
ISSN: ['2046-2069']
DOI: https://doi.org/10.1039/d3ra02371k