Efficacy of pipelle endometrial sampling in diagnosing endometrial pathologies in postmenopausal women with asymptomatic thick endometrium in comparison to fractional curettage

Objective: To evaluate the efficacy of pipelle endometrial sampling (PES) in diagnosing pathologies patients with asymptomatic thick endometrium compared to fractional curettage (FC). Methods: A prospective, comparative, observational study was conducted, involving 100 postmenopausal women thickened endometrium. Demographic characteristics, clinical features, and transvaginal ultrasound measurements were recorded. PES performed as an outpatient procedure, followed by confirmatory FC under general anesthesia. Histopathological examination conducted for both samples. Diagnostic accuracy, pain scores, association hyperplasia carcinoma assessed. Results: The mean age participants 56.7±2.8 years, a body mass index 29.6±3.6 kg/m2. thickness 14.3±2.9 mm. yielded 73 (73%) adequate samples, while 87 (87%) Pain scores significantly lower (3.23±1.23 vs. 6.48±1.54, respectively, p < 0.001). demonstrated sensitivity rate 81.25% specificity 100% hyperplasia, 60% carcinoma. Conclusions: Pipelle is effective well-tolerated method