Efficacy of Pimecrolimus 1% Cream in Various Clinical Forms of Atopic Dermatitis
نویسندگان
چکیده
منابع مشابه
Pimecrolimus 1% cream (Elidel) for atopic dermatitis.
Pimecrolimus is an immunomodulating medication that inhibits production of inflammatory cytokines in the skin and this compound was specifically developed for the treatment of inflammatory skin diseases. Phase II and III clinical trials with the topical formulation of pimecrolimus (Elidel cream, Novartis) have shown that it is safe and effective for use in patients with atopic dermatitis (AD). ...
متن کاملSystemic exposure, tolerability, and efficacy of pimecrolimus cream 1% in atopic dermatitis patients.
AIMS To measure pimecrolimus blood concentrations and to evaluate tolerability and efficacy in children and infants treated topically for atopic dermatitis with pimecrolimus cream 1% for three weeks. METHODS Three open label, non-controlled, multiple topical dose studies were conducted in children aged 8-14 years (study A, ten patients), and in infants aged 8-30 months (study B, eight patient...
متن کاملEfficacy and safety of pimecrolimus cream in the long-term management of atopic dermatitis in children.
OBJECTIVE Pimecrolimus cream (SDZ ASM 981), a nonsteroid inhibitor of inflammatory cytokines, is effective in atopic dermatitis (AD). We assessed whether early treatment of AD signs/symptoms with pimecrolimus could influence long-term outcome by preventing disease flares. METHODS Early intervention with pimecrolimus was compared with a conventional AD treatment strategy (ie, emollients and to...
متن کاملPimecrolimus Cream 1% in the Management of Atopic Dermatitis in Pediatric Patients: A Meta-Analysis
OBJECTIVE To evaluate the efficacy and safety of pimecrolimus cream 1% in the treatment of AD in the pediatric population. METHODS PubMed, EMBASE, Web of Science and Cochrane library databases were searched till July 2013. The randomized and nonrandomized blinded studies of pimecrolimus cream 1% applied twice daily with Jaded score ≥ 3 in pediatric patients with AD were included. The efficacy...
متن کاملRetraction: Pimecrolimus Cream 1% in the Management of Atopic Dermatitis in Pediatric Patients: A Meta-Analysis
After the publication of the article, a group of readers raised concerns about several aspects of the methodology for the metaanalysis and the interpretation of the results (http://www.plosone. org/article/comments/info%3Adoi%2F10.1371%2Fjournal.pone. 0093095). Upon follow-up with the authors and consultation with editorial board members, the following concerns have been identified: * The inter...
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ژورنال
عنوان ژورنال: TURKDERM
سال: 2010
ISSN: 1019-214X
DOI: 10.4274/turkderm.44.83