Efficacy of immune therapy in early experimental Naegleria fowleri meningitis
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چکیده
منابع مشابه
Naegleria Fowleri in Thailand, 2003
Between 1988 and 2003, Naegleria fowleri was studied extensively in Thailand. The distribution of N. fowleri has been studied in many provinces since 1988. During 2001-2003, we received financial support from Mahidol University to study the distribution of pathogenic Naegleria spp in water reservoirs in central, northern, and western parts of Thailand. With these funds, research was conducted i...
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A 7-year-old boy with no prior illness or altered immunity presented to the emergency department with a 36-hour history of fever (103.7°F), emesis, headache, and lethargy. The patient had a history of swimming in a local lake the week before presentation. Physical examination revealed nuchal rigidity. Computed tomography (CT) of the head was normal. A lumbar puncture revealed a cerebrospinal fl...
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Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 14, No. 9, September 2008 1499 Most of the patients whose cases were diagnosed in Buenos Aires, including 5 who required hospitalization, were referred to Muñiz Hospital. Built a century ago, Muñiz Hospital comprises a number of independent pavilions surrounded by a spacious garden, where mosquitoes thrive, especially in summer. Thus, vector...
متن کاملInnate resistance of mice to experimental infection with Naegleria fowleri.
The mouse system provides an excellent model for studying host resistance to Naegleria fowleri, the agent of primary amoebic meningoencephalitis. Innate resistance to infection with N. fowleri was examined with respect to infecting dose and the age, sex, and strain of mice. Intravenous inoculation with 10(7) amoebae per mouse produced 100% mortality in 9 days, whereas inoculation with fewer amo...
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Amoebae of Naegleria fowleri nN68 became elongated flagellated cells 150 to 180 min after subculture to non-nutrient buffer. N. fowleri NF69 did not become elongated or flagellated under these conditions. Electron microscopic examination of N. fowleri confirmed that it is a typical eucaryotic protist with a distinct nuclear envelope and prominent nucleolus, numerous vacuoles and cytoplasmic inc...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1987
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.55.5.1289-1293.1987