Efficacy of Autologous Serum with Antihistamine Therapy in the Treatment of Chronic Urticaria

Objective: To compare the efficacy of autologous serum with Antihistamine therapy in treating chronic urticaria.
 Study Design: Quasi-experimental study.
 Place and Duration Study: Dermatology Department, Pak Emirate Military Hospital, Rawalpindi Pakistan, from Jul 2018 to Jan 2019.
 Methodology: One hundred four patients urticaria (≥3 times/ week for ≥6 weeks) ages ranging 16 70 years were assigned treatment groups using a lottery method. i.e., Group-A (autologous therapy) Group-B(Antihistamine therapy). During eight weeks therapy, weekly Urticaria Activity Scoring (UAS-7) was utilized quantify response terms number weals pruritus.
 Results: Of 104 patients, 75(72.12%) females, 29(27.88%) males. Sixty-nine between 18 35 age, mean age 37.79±10.15 38.04±10.98 Group-B. Efficacy seen 40(76.92%) while Group-B (Antihistamine it 25(48.08%) patients(p-value =0.002).
 Conclusion: Autologous is more effective than urticaria.