Efficacy and Tolerability of Peginterferon alpha-2a and Peginterferon alpha-2b in Iranian Patients With Chronic Hepatitis C
نویسندگان
چکیده
منابع مشابه
efficacy and tolerability of peginterferon alpha-2a and peginterferon alpha-2b in iranian patients with chronic hepatitis c
conclusions there was no significant difference in the efficacy of peginterferon-alpha-2a and peginterferon-alpha-2b in iranian patients. physicians might choose the treatment regimen for every individual concerning the differences in side effects of peginterferons. background nearly 0.5% of iranians are infected with hcv. peginterferon-alpha-2a and peginterferon-alpha-2b are the two available ...
متن کاملEfficacy and Tolerability of Peginterferon alpha-2a and Peginterferon alpha-2b in Iranian Patients With Chronic Hepatitis C
BACKGROUND Nearly 0.5% of Iranians are infected with HCV. Peginterferon-alpha-2a and Peginterferon-alpha-2b are the two available types of interferon for the treatment of hepatitis C. Comparing the results of these two treatments is still a challenge. OBJECTIVES The aim of this study was to compare the results of Peginterferon-alpha-2a and Peginterferon-alpha-2b in Iranian patients with chron...
متن کامل[Peginterferon alpha-2b in patients with chronic hepatitis C].
150 adult patients were assigned pegylated interferon alpha-2b (once weekly 1.5 microg/kg) plus ribavirin (800-1200 mg depending on bodyweight). The treatment lasted 52 weeks and was completed by 139 persons (92.7%). Because of adverse events the treatment was interrupted in 7 persons, 4 other persons resigned. Periodical reduction of pegylated interferon doses was necessary in 19% and the redu...
متن کاملArea-under-the-curve for peginterferon alpha-2a and peginterferon alpha-2b is not related to body weight in treatment-naive patients with chronic hepatitis C.
One reason for dosing a drug by body weight is to reduce interpatient variability in clinical response. This study evaluated the relationship between body weight and drug exposure for peginterferon alpha-2a and peginterferon alpha-2b used in combination with ribavirin for treating patients with chronic hepatitis C. These two products are dosed differently: peginterferon alpha-2a is flat-dosed a...
متن کاملEfficacy and Safety of Low-Dose Peginterferon Alpha-2a Plus Ribavirin on Chronic Hepatitis C
Background. The purpose of this study was to assess the efficacy and safety of low-dose peg-IFN α-2a plus ribavirin on the treatment of patients with chronic hepatitis C virus (HCV) infection. Patients and Methods. A total of 243 HCV patients treated with different doses of peg-IFN α-2a plus ribavirin were stratified into three groups. End-of-treatment response (ETR) and sustained viral respons...
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ژورنال
عنوان ژورنال: Hepatitis Monthly
سال: 2015
ISSN: 1735-143X,1735-3408
DOI: 10.5812/hepatmon.30780