Efficacy and safety of statins. Medication choice specifics
نویسندگان
چکیده
منابع مشابه
Clinical efficacy and safety of statins in managing cardiovascular risk
Since their introduction in the 1980s, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) have emerged as the one of the best-selling medication classes to date, with numerous trials demonstrating powerful efficacy in preventing cardiovascular outcomes. As our understanding of low-density lipoprotein cholesterol (LDL-C) and atherosclerosis continues to grow, the conc...
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15 صفحه اولSafety of Statins
Statin monotherapy is generally well tolerated, with a low frequency of adverse events. The most important adverse effects associated with statins are myopathy and an asymptomatic increase in hepatic transaminases, both of which occur infrequently. Because statins are prescribed on a long-term basis, however, possible interactions with other drugs deserve particular attention, as many patients ...
متن کاملCo-Medication of Statins with Contraindicated Drugs
BACKGROUND The concomitant use of cytochrome P450 3A4 (CYP3A4) metabolized statins (simvastatin, lovastatin, and atorvastatin) with CYP3A4 inhibitors has been shown to increase the rate of adverse events. OBJECTIVE This study was performed to describe the co-medication prevalence of CYP3A4-metabolized statins with contraindicated drugs. METHODS The patients aged 40 or older receiving CYP3A4...
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A medication safety incident is defined by the National Patient Safety Agency (NPSA) as: ‘any unintended or unexpected incident which could have or did lead to harm for one or more patients’ (NPSA, 2007:9). These incidents can occur at each stage of the process involved in the delivery of medicines to patients, i.e. prescribing (including transcribing or physician ordering), dispensing, prepara...
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ژورنال
عنوان ژورنال: Kardiologiia: vid nauky do praktyky
سال: 2018
ISSN: 2312-7015
DOI: 10.30702/card:sp.2018.09.032/05