Efficacy and Safety of Alitretinoin for Chronic Hand Eczema in Korean Patients
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چکیده
منابع مشابه
Efficacy and Safety of Alitretinoin for Chronic Hand Eczema in Korean Patients
BACKGROUND Chronic hand eczema (CHE) tends to be refractory to conventional therapy. Previous clinical trials have found that a 24-week treatment course of oral alitretinoin is effective and well tolerated for CHE treatment. OBJECTIVE The aim of this study was to investigate the efficacy and safety of oral alitretinoin in Korean CHE patients. METHODS A total of 27 patients with moderate to ...
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2014 Chronic hand eczema (CHE), an inflammatory skin disease, places heavy psychosocial and economic burden on the affected individual and society as a whole. Patch testing is recommended to identify potential causative allergens in each patient. Efficacy of traditional topical treatments render the management of CHE challenging. Oral alitretinoin (9-cis-retinoic acid) is a new drug for the tre...
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Alitretinoin is a new oral retinoid authorized for use in grownups that have severe chronic hand eczema (CHE). A comprehensive search to solicit all studies of alitretinoin for the treatment of CHE. A comprehensive search to solicit all studies of alitretinoin for the treatment of CHE including randomized controlled trials (RCTs) or uncontrolled trials, re-treatment studies, open-label studies,...
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Background Alitretinoin is a vitamin A derivative. It’s a pan-agonist of Retinoic Acid Receptors and Retinoid X Receptors. It interferes with keratinocytes’ proliferation and differentiation and exerts immunomodulatory and anti-inflammatory activity. Its clinical efficacy in the treatment of chronic hand eczema is well demonstrated. Recently, various case reports and case series pointed out its...
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ژورنال
عنوان ژورنال: Annals of Dermatology
سال: 2016
ISSN: 1013-9087,2005-3894
DOI: 10.5021/ad.2016.28.3.364