Effects of the combination of metyrapone and oxazepam on cocaine and food self-administration in rats

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Effects of the combination of metyrapone and oxazepam on cocaine and food self-administration in rats.

For several years, our laboratory has investigated the role for the HPA axis in cocaine reinforcement. Two classes of drugs that we have studied include corticosterone synthesis inhibitors (e.g., metyrapone) and benzodiazepine receptor agonists (e.g., oxazepam). In the experiments described in this manuscript, we tested the effects of various doses of metyrapone and oxazepam against several dos...

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ژورنال

عنوان ژورنال: Pharmacology Biochemistry and Behavior

سال: 2008

ISSN: 0091-3057

DOI: 10.1016/j.pbb.2008.07.005