Effects of sex hormones on haloperidol catalepsy in mice
نویسندگان
چکیده
منابع مشابه
Piracetam reverses haloperidol-induced catalepsy in mice
Results: Th e administration of haloperidol (2 mg/kg, IP) resulted in signifi cant catalepsy. Piracetam (in dosages of 50, 100, and 300 mg/kg) given IP at the time of haloperidol administration reduced the duration of catalepsy by 24.4%, 32.3%, and 48.2%, respectively. Piracetam given as a 30-min pretreatment reduced the duration of catalepsy by 59.5%, 72.3%, and 78.2%, respectively. Vinpocetin...
متن کاملEffect of Tribulus terrestris on Haloperidol-induced Catalepsy in Mice
Haloperidol, an antipsychotic drug, leads to the development of a behavioural state called catalepsy, in which the animal is not able to correct an externally imposed posture. In the present study we have attempted to evaluate the anticataleptic effect of Tribulus terrestris on haloperidol-induced catalepsy in albino mice. Mice were allocated to four groups, each group containing six animals. B...
متن کاملEffects of Cannabis sativa extract on haloperidol-induced catalepsy and oxidative stress in the mice
Haloperidol is a classic antipsychotic drug known for its propensity to cause extrapyramidal symptoms due to blockade of dopamine D2 receptors in the striatum. Interest in medicinal uses of cannabis is growing. Cannabis sativa has been suggested as a possible adjunctive in treatment of Parkinson's disease. The present study aimed to investigate the effect of repeated administration of an extrac...
متن کاملStrain dependent effects of sex hormones on hepatocarcinogenesis in mice.
In order to study the interaction of genetic and hormonal factors during murine hepatocarcinogenesis, we compared the number of liver tumors induced by treatment of 12-day-old mice with N,N-diethylnitrosamine (DEN) (0.05 mumol/g body wt) in intact mice and animals gonadectomized at 8 weeks of age from the three inbred strains, C3H/HeJ (C3H), C57BL/6J (B6), and C57BR/cdJ (BR). At 50 weeks of age...
متن کاملEffect of ethanolic leaf extract of Ocimum sanctum on haloperidol-induced catalepsy in albino mice
Neuroleptic drugs used in the treatment of schizophrenia and other affective disorders are known to produce extrapyramidal side effects. Catalepsy induced by these drugs in Department of Pharmacology, Kasturba Medical College, animals has been used as a model for the extrapyramidal side effects associated with Mangalore 575 001, Karnataka, antipsychotic agents in human beings. In the present st...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1984
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)62539-4