Effects of Repeated Botulinum Toxin Treatment for Sialorrhea in Patients with Parkinson’s Disease

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Effects of Repeated Botulinum Toxin Treatment for Sialorrhea in Patients with Parkinson's Disease.

INTRODUCTION To evaluate the efficacy and adverse effects of repeated onabotulinumtoxinA (BoNT-A) treatment in patients suffering from Parkinson's disease (PD) with sialorrhea. METHODS A retrospective analysis of 16 patients with sialorrhea treated with BoNT-A at our movement disorders outpatient clinic was conducted from February 2009 to September 2013. A patient with adult cerebral palsy an...

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Botulinum toxin A in the treatment of sialorrhea.

OBJECTIVE To review the efficacy and safety of botulinum toxin A (BTX) in the treatment of sialorrhea. DATA SOURCES A PubMed search and reference list review was performed to find clinical trials on BTX in the treatment of sialorrhea. The search was limited to English-language trials involving human subjects. Articles from 1965 to October 2006 were searched, using key words botulinum, botulin...

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Botulinum toxin type A treatment for Parkinsonian patients with moderate to severe sialorrhea.

PURPOSE To investigate the effect of botulinum toxin type A (BTX-A; Botox) in reducing saliva in patients with Parkinsonism. METHODS Fifteen patients with clinical diagnosis of idiopathic Parkinson's disease, dementia with Lewy bodies, or multiple system atrophy were enrolled in this open clinical trial. A total of 40-unit dose of Botox was injected into the bilateral parotid and submandibula...

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Botulinum Toxin A in the Treatment of Sialorrhea in Children with Cerebral Palsy

INTRODUCTION Sialorrhea is problematic for many neurologically impaired patients. They suffer from excessive salivation because of inadequate oral motor control or swallowing dysfunction [1]. Persistent sialorrhea creates major hygienic and psychosocial problems. Maceration of skin around the mouth and neck may result in secondary bacterial infection. In addition, drooling is not a respectable ...

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ژورنال

عنوان ژورنال: Noro Psikiyatri Arsivi

سال: 2015

ISSN: 1300-0667,1309-4866

DOI: 10.5152/npa.2015.7477