Effects of low molecular weight polysaccharide from <em>Sargassum thunbergii</em> against palmitic acid-induced intracellular lipid accumulation in 3T3-L1 adipocyte and HepG2 cells

Low molecular weight polysaccharides can be isolated from Sargassum thunbergii (LMPST) and in vitro experiments were conducted to evaluate the inhibitory effects on lipids. Two natures of LMPST attained from Sargassum appraised their palmitic acid induced lipid accretion HepG2, 3T3-L1 cells. treatment lessened deposition intracellular free fatty triglyceride intensities PA-treated above mentioned The mechanistic study publicized that LMPST2 significantly suppressed adipogenesis stimulated cells occupied lipolysis pathway. Furthermore, HepG2 cells, oxidation was increased by LMPST2. Given these constructive properties thunbergii, is a potential candidate for diminishing lipids, therapeutic agent those conditions.