Effects of environmental and pharmacological manipulations on a novel delayed nonmatching-to-sample ‘working memory’ procedure in unrestrained rhesus monkeys
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چکیده
منابع مشابه
Scopolamine effectS Under a titrating-delayed- nonmatching-to-poSition procedUre
In a study of working memory, the performance of rats under titrating-delayednonmatching-to-position (TDNMTP) procedures was examined. Overall accuracy and the number of trials completed were inversely related to titration value, whereas the highest delay attained was directly related to titration value. When given intraperitoneally, scopolamine significantly reduced the highest delay attained ...
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از گذشته تا کنون، تحقیقات بسیاری صورت گرفته است که همگی به گونه ای بر مثمر ثمر بودن استفاده از استراتژی های یادگیری لغت در یک زبان بیگانه اذعان داشته اند. این تحقیق به بررسی تاثیر دو روش مختلف آموزش واژگان انگلیسی (کلیدی و بافتی) بر تلفظ و دانش لغوی فراگیران ایرانی زیر متوسط زبان انگلیسی و بر ماندگاری آن در حافظه می پردازد. به این منظور، تعداد شصت نفر از زبان آموزان ایرانی هشت تا چهارده ساله با...
15 صفحه اولNormal Performance of Fmr1 Mice on a Touchscreen Delayed Nonmatching to Position Working Memory Task.
Fragile X syndrome is a neurodevelopmental disorder characterized by mild-to-severe cognitive deficits. The complete absence of Fmr1 and its protein product in the mouse model of fragile X (Fmr1 KO) provides construct validity. A major conundrum in the field is the remarkably normal performance of Fmr1 mice on cognitive tests in most reports. One explanation may be insufficiently challenging co...
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BACKGROUND AND PURPOSE Male cynomolgus monkeys (n = 10) were subjected to varying durations of global cerebral ischemia to determine the relation between dose (ischemic duration) and response (outcome). METHODS Each monkey was anesthetized with halothane, and global cerebral ischemia was produced by a neck tourniquet and trimethaphan-induced hypotension. The animal was subjected to 3 (n = 3),...
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The neuropeptide oxytocin has been shown to have prosocial effects in both monkeys and humans, leading to its proposed use as a treatment for social disorders in humans such as Autism Spectrum Disorder (ASD). The opioid system interacts with the oxytocinergic system in an antagonistic manner, so that inactivation of the opioid system causes an increase in oxytocin levels. In this experiment, we...
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ژورنال
عنوان ژورنال: Journal of Neuroscience Methods
سال: 2015
ISSN: 0165-0270
DOI: 10.1016/j.jneumeth.2015.05.009