Effects of chronic hypoxia on cardiac function measured by pressure-volume catheter in fetal chickens

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Effects of chronic hypoxia on cardiac function measured by pressure-volume catheter in fetal chickens.

Hypoxia is a common component of many developmental insults and has been studied in early-stage chicken development. However, its impact on cardiac function and arterial-ventricular coupling in late-stage chickens is relatively unknown. To test the hypothesis that hypoxic incubation would reduce baseline cardiac function but protect the heart during acute hypoxia in late-stage chickens, white L...

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The Effects of Chronic Hypoxia on Cardiac Function Measured by Pressure-Volume

7 Sonnet S Jonker, George D Giraud, Herbert M Espinoza, Erica N Davis, Dane A Crossley II. 8 Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon; Department of 9 Physiology and Pharmacology, Oregon Health & Science University, Portland, Oregon; VA Portland 10 Health Care System, Portland, Oregon; Department of Biological Sciences, University of North Texas, 11 ...

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Fetal in vivo continuous cardiovascular function during chronic hypoxia

Although the fetal cardiovascular defence to acute hypoxia and the physiology underlying it have been established for decades, how the fetal cardiovascular system responds to chronic hypoxia has been comparatively understudied. We designed and created isobaric hypoxic chambers able to maintain pregnant sheep for prolonged periods of gestation under controlled significant (10% O2) hypoxia, yield...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

سال: 2015

ISSN: 0363-6119,1522-1490

DOI: 10.1152/ajpregu.00484.2014